Msm

Methylsulfonylmethane

Methylsulfonylmethane(MSM) which is a naturally occurring constituent of the various forms of organic sulfur, found in many foods, fruits, vegetables, dairy products, meat and fish, is part of one of the fundamental biological cycles of our planet that, starting from the oceans where, several hundred million years ago, algae and plankton began to release it along with high homologous components in gaseous form, releasing them into the atmosphere. Even today these constituents captured by plants through rain will go on to form part of the backbone of animal and plant biology.

In our bodies for example, sulfur is the fourth most present mineral, where it underlies support functions in general, keeping cells more permeable, promoting toxin elimination, supporting joint function, and promoting better health for nails and hair. Because of the characteristics mentioned and more, we can say that the discovery of the role of biological sulfur in health can be considered among the greatest advances in orthomolecular medicine in the last fifty years. Since the systemic concentration of MSM declines with increasing age, probably due to change in diet or body metabolism it is clear that its supplementation is to be considered positively.

BIBLIOGRAPHY

Butawan, Matthew, Rodney L. Benjamin, and Richard J. Bloomer. "Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement." Nutrients 9.3 (2017): 290. PMC. Web. 14 Jan. 2018.

Jacob, S.W: The Current Status of MSM in Medicine. Am. Acad. Med. Prev., 1983.

 Jacob, S.W. and Herschler, R.J.: Introductory Remarks: Dimethylsulfoxide after Twenty Years. Ann. N.Y. Acad. Sci.: 1983.

Munck-Khoe, L. K. de: Vitaminen, Hardware of Software? Deel 1. Ortho 14(5), 1996: 204-211.

 Brien S, Prescott P, Bashir N, Lewith H, Lewith G. Systematic review of the nutritional supplements dimethyl sulfoxide (DMSO) and methylsulfonylmethane (MSM) in the treatment of osteoarthritis. Osteoarthritis Cartilage. 2008 Nov;16(11):1277-88. Epub 2008 Apr 15.

 Childs SJ. Dimethyl sulfone (DMSO2) in the treatment of interstitial cystitis. Urol Clin North Am 1994;21:85-88.

 Murav'ev IuV, Venikova MS, Pleskovskaia GN, et al. Effect of dimethyl sulfoxide and dimethyl sulfone on a destructive process in the joints of mice with spontaneous arthritis [in Russian].Patol Fiziol Eksp Ter. 1991;2:37-39

Debbi EM, Agar G, Fichman G, et al. Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study. BMC Complement Altern Med.2011;11:50.

Kim LS, Axelrod LJ, Howard P, Buratovich N, Waters RF - Osteoarthritis Cartilage. 2006 Mar;14(3):286-94 Epub 2005 Nov 23. - Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial.